Contents
Contributors xi Introduction to the Review of Psychiatry Series xv John M. Oldham, M.D., and Michelle B. Riba, M.D., M.S., Series Editors
Chapter 1 Recurrent Depression: Its Overwhelming Burden 1 John F. Greden, M.D. Widespread Prevalence 3 Early Symptom Onset 4 Underdiagnosis and Undertreatment 5 Genetic Vulnerability 7 Frequent Recurrences 8 Inadequate Emphasis on Recurrence Prevention 10 Poor Maintenance Treatment Adherence and Stigma 11 Brain Tissue Degeneration 12 Strategies to Prevent Recurrences and Reduce the Burden of MDD 14 References 15
Chapter 2 Recurrent Depression in Women Throughout the Life Span 19 Sheila M. Marcus, M.D. Heather A. Flynn, Ph.D. Elizabeth A. Young, M.D. Neera Ghaziuddin, M.D. Sharon Mudd, M.S., R.N., C.S., N.P. Depression in Adolescence 19
Depression in Pregnancy and the Postpartum Period 27 Depression in Midlife 40 The Need for More Research 48 Conclusion 50 References 50
Chapter 3 Chronic and Recurrent Depression: Pharmacotherapy and Psychotherapy Combinations 59 Robert Boland, M.D. Martin B. Keller, M.D. Importance of Adequate Treatment 60 Medication Treatment 61 Combination Treatment 65 Current Issues, Unanswered Questions 74 Conclusion 77 References 78
Chapter 4 Prevention of Recurrences in Patients With Bipolar Disorder: The Best of the Old and the New 81 Charles L. Bowden, M.D. Cheryl L. Gonzales, M.D. Goals of Care for Patients With Bipolar Disorder 81 Pharmacotherapy 89 Combination Treatment 97 Summary 98 References
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Contributors xi Introduction to the Review of Psychiatry Series xv John M. Oldham, M.D., and Michelle B. Riba, M.D., M.S., Series Editors
Chapter 1 Recurrent Depression: Its Overwhelming Burden 1 John F. Greden, M.D. Widespread Prevalence 3 Early Symptom Onset 4 Underdiagnosis and Undertreatment 5 Genetic Vulnerability 7 Frequent Recurrences 8 Inadequate Emphasis on Recurrence Prevention 10 Poor Maintenance Treatment Adherence and Stigma 11 Brain Tissue Degeneration 12 Strategies to Prevent Recurrences and Reduce the Burden of MDD 14 References 15
Chapter 2 Recurrent Depression in Women Throughout the Life Span 19 Sheila M. Marcus, M.D. Heather A. Flynn, Ph.D. Elizabeth A. Young, M.D. Neera Ghaziuddin, M.D. Sharon Mudd, M.S., R.N., C.S., N.P. Depression in Adolescence 19
Depression in Pregnancy and the Postpartum Period 27 Depression in Midlife 40 The Need for More Research 48 Conclusion 50 References 50
Chapter 3 Chronic and Recurrent Depression: Pharmacotherapy and Psychotherapy Combinations 59 Robert Boland, M.D. Martin B. Keller, M.D. Importance of Adequate Treatment 60 Medication Treatment 61 Combination Treatment 65 Current Issues, Unanswered Questions 74 Conclusion 77 References 78
Chapter 4 Prevention of Recurrences in Patients With Bipolar Disorder: The Best of the Old and the New 81 Charles L. Bowden, M.D. Cheryl L. Gonzales, M.D. Goals of Care for Patients With Bipolar Disorder 81 Pharmacotherapy 89 Combination Treatment 97 Summary 98 References
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